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Bcl-xL promoter has two WT1 binding web pages 5'-GCGGGGGAGC-3' and 5'GAGCGGGAGT-3', which happen to be comparable to the consensus WTE motif 5'-GCGTGGGAGT-3' [12] at positions -307 to -298 and -301 to -292 upstream of the transcription commence web-site of BclxL gene (Fig 5A remaining). Bcl-2 promoter also incorporates five WT1 binding internet sites with all the consensus sequence 5'-GNGNGGGNG-3'
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Al., 1996, 1999). Mesp1 lineage tracing experiments in mice revealed that practically all cells in the future heart at the same time as cells of the major vessels derived from cells that had expressed Mesp1 at one particular point during embryonic development (Saga et al., 1999, 2000). In addition to getting the earliest marker of cardiovascular improvement, Mesp1 also plays an extremely critical
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